Curt I. Civin, pediatric oncologist and stem cell researcher (1997) :: Smithsonian Lemelson Center
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Oral & video history documentation

The Lemelson Center's oral and video history projects increase historical documentation on invention and innovation in the United States.
Above: Guitarist G.E. Smith is featured in the Electric Guitar Video Documentation Project. Smithsonian photo by Jeff Tinsley.

Full descriptions of the following collections may be found by searching the archives and manuscripts section of SIRIS, the Smithsonian Institution Research Information System. Unless otherwise noted, all collections are housed in the NMAH Archives Center. For further information, contact the Archives Center Reference Desk.

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Oral & video history documentation is listed in alphabetical order by subject of interview. Date of interview is in parentheses.

 

Curt I. Civin, pediatric oncologist and stem cell researcher (1997)

In the 1970s when Civin began stem cell research, little was known about progenitors, the cells of all other blood lineage. Civin thought that stem cells had their own identifying surface proteins. To test this, he immunized mice with leukemia cells, some of which he supposed might have that peculiar protein, and then harvested the resulting immunoglobulins and reproduced them as monoclonal antibodies. In 1981, Civin discovered an antibody that bound to 1% of marrow cells. Video footage includes an interview with Curt I. Civin about his discovery of the cell surface protein that makes stem cell selection possible; and interviews with Kenneth Kinsler and Bert Vogelstein. The prototype of the stem cell selector instrument is located in the Division of Science, Medicine, and Society collections, NMAH.

0.25 cu. ft.: 1 box containing original videos.

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